LUPUS
TARGETED
HER.

TARGET LUPUS
NOW WITH
BENLYSTA.

Icon: Target BLyS

Targets underlying disease1,2

SEE HOW BENLYSTA WORKS

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Improves key
clinical outcomes3-6

SEE LUPUS DATA

SEE LUPUS NEPHRITIS DATA

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Reduction of organ
damage progression7

SEE ORGAN DAMAGE DATA

BENLYSTA IS PROVEN TO REDUCE DISEASE ACTIVITY IN PATIENTS WITH LUPUS

Up to

61%

61%

of patients had reduced disease
activity (SRI-4) at Week 523-5*

 

BENLYSTA IS PROVEN TO IMPROVE COMPLETE RENAL RESPONSE IN PATIENTS WITH LUPUS NEPHRITIS

74%

more likely to achieve complete renal response6
(OR=1.74; 95% CI: 1.11, 2.74; P=0.0167)

More patients on BENLYSTA + ST (n=223) vs placebo + ST (n=223) achieved CRR at Week 104; 30% vs 20%, respectively.

 

BENLYSTA SIGNIFICANTLY REDUCED RISK OF RENAL-RELATED EVENTS OR DEATH6,8

49%

reduction in risk of renal-related events or death
(HR=0.51; 95% CI: 0.34, 0.77; P=0.0014)

Less patients with lupus nephritis on BENLYSTA + ST (n=223) vs placebo + ST (n=223) experienced a renal-related event or death; 16% vs 28%, respectively.

* SRI-4 response rate at Week 52 (primary endpoint).

† When excluding deaths (BENLYSTA=1, ST=2), the percentage of patients with a renal-related event was 15% vs 27%, respectively (HR=0.51; 95% CI: 0.34, 0.78).

CI = confidence interval; HR = hazard ratio; SRI = SLE Responder Index; ST = standard therapy.

 

WELL-ESTABLISHED SAFETY BASED ON THE LARGEST CLINICAL TRIAL PROGRAM IN LUPUS AND LUPUS NEPHRITIS

7000+

patients with lupus have been
included in trials of BENLYSTA,
including a clinical trial in
patients with lupus nephritis
(N=448)3-6,9-11

Organ damage

The impact of BENLYSTA was evaluated in a real-world analysis of organ damage progression.

Icon: Silhouette highlighting organ domains

Improvements in organ domains

Improvements in multiple organ systems, including skin, joint, and kidney.

Results are descriptive.

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Target underlying disease.
Choose BENLYSTA now.

Image: Woman with yellow circle
Image: Woman with yellow circle