BY THE TIME LUPUS
NEPHRITIS IS DIAGNOSED,
KIDNEY DAMAGE MAY
ALREADY BE SEVERE1

Approximately

40%

of patients with lupus will develop lupus nephritis2,3*

 

Approximately

20%

of patients with lupus
nephritis will progress to ESKD
within 10 years of diagnosis4

45%

of patients with lupus nephritis experience renal flares despite receiving immunosuppressive therapy1,7†

With each renal flare, there is irreversible nephron loss – shortening the kidney’s life span and increasing the risk of ESKD1,5,6†

Potential impact of lupus nephritis on kidney life span

Potential impact of lupus nephritis on kidney lifespan chart

45%

of patients with lupus nephritis experience renal flares
despite receiving immunosuppressive therapy1,7†

Potential impact of lupus nephritis on kidney lifespan chart

Adapted with permission from Anders H-J, et al., 2020.

It is critical to reduce the number of renal flares to prevent progression to ESKD and the need for dialysis1,6

* Including patients with and without biopsy-proven lupus nephritis.

† Renal flares are defined as a rise in serum creatinine level and/or proteinuria, abnormal urinary sediment, or reduction in creatinine clearance.1,6

ESKD = end-stage kidney disease.